THE HUMAN LEWIS BLOOD GROUP FUCOSYLTRANSFERASE PROMOTER. † 898
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چکیده
منابع مشابه
Co - purification of the Lewis Blood Group N - Acetylglucosaminide a 1 + 4 Fucosyltransferase and an N - Acetylglucosaminide a 1 + 3 Fucosyltransferase from Human Milk
The Lewis blood group-specified N-acetylglucosaminide a1 + 4 fucosyltransferase and an N-acetylglucosaminide a1 + 3 fucosyltransferase have been copurified over 500,000-fold from human milk by affinity chromatography on GDP-hexanolamine agarose. The purified enzyme preparation migrates as two major bands on sodium dodecyl sulfate-polyacrylamide gel electrophoresis with apparent M, = 53,000 and ...
متن کاملAnalysis of Lewis fucosyltransferase genes from the human gastric mucosa of Lewis-positive and -negative individuals.
The expression of Lewis fucosyltransferase (FT) mRNA was examined in gastric mucosa from two Lewis-positive [Le(+)] and two Lewis-negative [Le(-)] individuals. Northern blot analysis demonstrated that levels of mRNA were similar in both Le(+) and Le(-) gastric mucosa. We isolated the protein-coding region of the Lewis FT cDNA from Le(+) and Le(-) gastric mucosa by polymerase chain reaction (PCR...
متن کاملSchistosoma mansoni α1,3-fucosyltransferase-F generates the Lewis X antigen.
Genetic evidence suggests that the Schistosoma mansoni genome contains six genes that encode α1,3-fucosyltransferases (smFuTs). To date, the activities and specificities of these putative fucosyltransferases are unknown. As Schistosoma express a variety of fucosylated glycans, including the Lewis X antigen Galβ1-4(Fucα1-3)GlcNAcβ-R, it is likely that this family of genes encode enzymes that are...
متن کاملThe Lewis blood group system in liver transplantation.
THE LEWIS blood group antigens Lea and Leb have been found on red blood cells (RBCs), in secretions and fluids such as saliva, alimentary tract juice, and urine, and in various tissues including renal tubular cells, collecting ducts, urothelium, and ductal or mucosal epithelium of the sweat glands, salivary glands, gastrointestinal tract, pancreas, uterus, cervix, and breast. l .s Hepatic bile ...
متن کاملAlteration of gibberellin response in transgenic tobacco plants which express a human Lewis fucosyltransferase.
In plants, Lewisa type N-glycans may be involved in cell-to-cell communication and recognition. N-glycoproteins harboring Lewisa glycotopes are mainly found in plasma membranes and cell walls. Some can be also involved in cell wall synthesis or the loosening process, and subsequently in cell elongation. In order to determine the potential role(s) of the alpha4-fucosylation during vegetative dev...
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ژورنال
عنوان ژورنال: Pediatric Research
سال: 1996
ISSN: 0031-3998,1530-0447
DOI: 10.1203/00006450-199604001-00920